Projini : Redesigning Chemistry for Agriculture

What if no new pesticides were developed in decades? This is the reality today, and it's having a severe impact on the global food supply. Over 30% of the world’s harvest is lost due to pests, costing billions and threatening food security.

The Challenge
Pests have developed resistance to current pesticides, much like cancer cells resist treatment in humans. Weeds and fungi, for example, can evade commonly used agents. Despite this, no new pesticides with innovative biological mechanisms have been developed in decades. This puts the world’s food supply at risk.

Our Mission

At ProJini AgChem, we are focused on discovering and developing new pesticides that target protein-protein interaction networks in pests, a completely novel mechanism of action. Our goal is to ensure sufficient food production for a growing global population by disrupting these essential cellular interactions in pests.

ProJini’s Solution

We’ve built a powerful pesticide-discovery engine using a cutting-edge platform that combines computational modeling with advanced biochemical and biophysical tools. This approach rapidly identifies the molecular and structural requirements for binding specific molecules to their target proteins.

Classic enzyme-small molecule interaction

• Targets with well-defined binding sites
• Easy to assay
• 300-500 Ų

Protein-protein interaction

• 'Undruggable' targets without clear binding sites
• Difficult to screen but essential for biological effects

• 1500 Ų